{"id":3301,"date":"2017-03-05T15:27:01","date_gmt":"2017-03-05T06:27:01","guid":{"rendered":"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=3301"},"modified":"2017-08-09T20:46:33","modified_gmt":"2017-08-09T11:46:33","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e9%87%8d%e8%a4%87%e3%81%af%e3%80%81%e9%a0%91%e5%81%a5%e6%80%a7%e3%81%a7%e3%81%af%e3%81%aa%e3%81%8f%e8%84%86%e5%bc%b1%e6%80%a7%e3%82%92%e9%85%b5%e6%af%8d%e3%81%ae%e3%82%bf","status":"publish","type":"post","link":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=3301","title":{"rendered":"\u907a\u4f1d\u5b50\u91cd\u8907\u306f\u3001\u9811\u5065\u6027\u3067\u306f\u306a\u304f\u8106\u5f31\u6027\u3092\u9175\u6bcd\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u4ed8\u4e0e\u3059\u308b\u3002"},"content":{"rendered":"<p class=\"title\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28183979\"><b>Gene duplication can impart fragility, not robustness, in the yeast protein interaction network.<\/b><\/a><\/p>\n<div class=\"supp\">\n<p class=\"desc\">Diss G, Gagnon-Arsenault I, Dion-Cot\u00e9 AM, Vignaud H, Ascencio DI, Berger CM, Landry CR.\u00a0<span class=\"jrnl\" title=\"Science (New York, N.Y.)\">Science<\/span>. 2017 Feb 10;355(6325):630-634. doi:10.1126\/science.aai7685. PMID:28183979<\/p>\n<\/div>\n<p>\u907a\u4f1d\u5b50\u304c\u91cd\u8907\u3059\u308b\uff08\u30b2\u30ce\u30e0\u4e0a\u3067\u540c\u3058\u907a\u4f1d\u5b50\u306e\u30b3\u30d4\u30fc\u304c\u5897\u3048\u308b\uff09\u3053\u3068\u304c\u9032\u5316\u306e\u539f\u52d5\u529b\u3068\u306a\u308b\u3068\u3044\u3046\u300c<a href=\"https:\/\/ja.wikipedia.org\/wiki\/%E9%81%BA%E4%BC%9D%E5%AD%90%E9%87%8D%E8%A4%87\" target=\"_blank\" rel=\"noopener\">\u907a\u4f1d\u5b50\u91cd\u8907\u8aac<\/a>\u300d\u306f\u3001\u5927\u91ce\u4e7e\u535a\u58eb\u306b\u3088\u3063\u3066\u63d0\u5531\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u8aac\u306f\u3001\u30b2\u30ce\u30e0\u751f\u7269\u5b66\u3084\u30b7\u30b9\u30c6\u30e0\u751f\u7269\u5b66\u306e\u767a\u5c55\u306b\u4f34\u3063\u3066\u3001\u591a\u69d8\u306a\u5074\u9762\u304b\u3089\u691c\u8a3c\u304c\u306a\u3055\u308c\u3001\u305f\u304f\u3055\u3093\u306e\u8208\u5473\u6df1\u3044\u767a\u898b\u306b\u3064\u306a\u304c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u907a\u4f1d\u5b50\u304c\u91cd\u8907\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u60f3\u50cf\u3057\u3084\u3059\u3044\u6700\u5927\u306e\u30e1\u30ea\u30c3\u30c8\u306f\u3001\u300c\u30d0\u30c3\u30af\u30a2\u30c3\u30d7\u300d\u3067\u3059\u3002\u540c\u3058\u6a5f\u80fd\u3092\u6301\u3064\u907a\u4f1d\u5b50\u304c\uff12\u3064\u3042\u308c\u3070\u3001\uff11\u3064\u304c\u58ca\u308c\u305f\u3068\u3057\u3066\u3082\u305d\u306e\u751f\u304d\u7269\u306f\u884c\u304d\u3066\u3044\u3089\u308c\u308b\u3002\u305f\u3060\u3001\u3053\u306e\u8003\u3048\u65b9\u306f\u3042\u307e\u308a\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\uff08\u30d0\u30c3\u30af\u30a2\u30c3\u30d7\u304c\u3042\u308b\u3053\u3068\u306b\u3088\u3063\u3066\uff09\u58ca\u308c\u3066\u3082\u4f55\u3082\u304a\u304d\u306a\u3044\u907a\u4f1d\u5b50\u304c\u305d\u3082\u305d\u3082\u30b2\u30ce\u30e0\u4e0a\u306b\u4fdd\u6301\u3055\u308c\u306b\u304f\u3044\u3001\u3042\u308b\u3044\u306f\u30d0\u30c3\u30af\u30a2\u30c3\u30d7\u3068\u3057\u3066\u307e\u3063\u305f\u304f\u540c\u3058\u6a5f\u80fd\u306e\u907a\u4f1d\u5b50\u3092\u4fdd\u6301\u3057\u7d9a\u3051\u308b\u3053\u3068\u306e\u30b3\u30b9\u30c8\u306e\u307b\u3046\u304c\u5927\u304d\u3044\u3001\u3068\u3044\u3046\u3088\u3046\u306a\u3053\u3068\u304c\u7406\u7531\u3068\u3057\u3066\u3042\u3052\u3089\u307e\u3059\u3002<\/p>\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u91cd\u8907\u3057\u305f\u907a\u4f1d\u5b50\u304c\u30b2\u30ce\u30e0\u4e0a\u306b\u4fdd\u6301\u3055\u308c\u7d9a\u3051\u308b\u305f\u3081\u306b\u306f\u3001\u4fdd\u6301\u305b\u3056\u308b\u3092\u3048\u306a\u3044\u7406\u7531\u304c\u3042\u308b\u304b\u3001\u91cd\u8907\u3057\u305f\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u304c\u6025\u901f\u306b\u5909\u5316\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u91cf\u306e\u52b9\u679c\u3084\u6a5f\u80fd\u5206\u5316\u3001\u65b0\u898f\u306e\u6a5f\u80fd\u7372\u5f97\u306a\u3069\u304c\u305d\u308c\u306b\u5f53\u305f\u308a\u307e\u3059\u3002<\/p>\n<p>\u3055\u3066\u3001\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001\u91cd\u8907\u907a\u4f1d\u5b50\u3092\u8907\u6570\u3082\u3064\u51fa\u82bd\u9175\u6bcd\u3092\u6750\u6599\u3068\u3057\u3066\u4f7f\u3044\u3001\u91cd\u8907\u907a\u4f1d\u5b50\u306e\u7247\u65b9\u304c\u58ca\u308c\u305f\u6642\u306b\u3001\u305d\u308c\u304c\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3092\u8abf\u3079\u307e\u3057\u305f\u3002<\/p>\n<p>\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u3042\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u5225\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u7d50\u5408\uff08\u76f8\u4e92\u4f5c\u7528\uff09\u3057\u306a\u304c\u3089\u6a5f\u80fd\u3057\u307e\u3059\u3002\u904e\u53bb\u306e\u91cd\u8907\u306e\u7d50\u679c\u751f\u3058\u305f\u907a\u4f1d\u5b50\u304c\u30b3\u30fc\u30c9\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u591a\u304f\u306f\u3001\u305d\u306e\u6a5f\u80fd\u5206\u5316\u306e\u7d50\u679c\u3001\u305d\u308c\u305e\u308c\u9055\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u3069\u3046\u3057\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\u898b\u3089\u308c\u307e\u3059\uff08\u4e0b\u56f3\uff09\u3002<\/p>\n<figure id=\"attachment_3303\" aria-describedby=\"caption-attachment-3303\" style=\"width: 580px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?attachment_id=3303\" rel=\"attachment wp-att-3303\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-3303 size-large\" src=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/2a14f403fc85c0a93c3ca215079cc9bf-973x1024.png\" width=\"580\" height=\"610\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/2a14f403fc85c0a93c3ca215079cc9bf-973x1024.png 973w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/2a14f403fc85c0a93c3ca215079cc9bf-285x300.png 285w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/2a14f403fc85c0a93c3ca215079cc9bf-768x809.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/2a14f403fc85c0a93c3ca215079cc9bf.png 1117w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><figcaption id=\"caption-attachment-3303\" class=\"wp-caption-text\">\u91cd\u8907\u3057\u305f\u907a\u4f1d\u5b50\uff08\u8d64\u3068\u9ec4\u8272\uff09\u304c\u30b3\u30fc\u30c9\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u5225\u3005\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3088\u3046\u306b\u306a\u308b\u3002\u5143\u8ad6\u6587Fig.1\u3092\u6539\u5909\u3002<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u91cd\u8907\u907a\u4f1d\u5b50\u306e\u7247\u65b9\u3092\u58ca\u3057\u305f\u6642\u306b\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u306e\u72b6\u614b\u304c\u3069\u3046\u306a\u308b\u304b\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u9ec4\u8272\u3092\u58ca\u3057\u305f\u6642\u306b\u3001\u8d64\u304c\u884c\u3063\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3069\u3046\u3044\u3046\u5f71\u97ff\u304c\u3042\u308b\u304b\u3068\u8a00\u3046\u3053\u3068\u3067\u3059\u3002\u53ef\u80fd\u6027\u3068\u3057\u3066\u306f\uff13\u3064\u3042\u308a\u307e\u3059\uff08\u4e0b\u56f3\uff09\u30021\uff09\u4f55\u3082\u8d77\u304d\u306a\u3044\u3001\u3064\u307e\u308a\u8d64\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u306f\u5f71\u97ff\u304c\u306a\u3044\u30022\uff09\u300c\u88dc\u511f\uff1aCompensation\u300d\u3001\u9ec4\u8272\u304c\u884c\u3063\u3066\u3044\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u3092\u8d64\u304c\u80a9\u4ee3\u308f\u308a\u3059\u308b\u30023)\u300c\u4f9d\u5b58\uff1aDependency\u300d\u3001\u9ec4\u8272\u3092\u58ca\u3057\u305f\u306e\u306b\u8d64\u306e\u76f8\u4e92\u4f5c\u7528\u307e\u3067\u7834\u7dbb\u3059\u308b\u3002<\/p>\n<figure id=\"attachment_3304\" aria-describedby=\"caption-attachment-3304\" style=\"width: 580px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?attachment_id=3304\" rel=\"attachment wp-att-3304\"><img decoding=\"async\" class=\"size-large wp-image-3304\" src=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/a9d273aa85aab5c1736fd66cacfccbad-1024x959.png\" alt=\"\" width=\"580\" height=\"543\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/a9d273aa85aab5c1736fd66cacfccbad-1024x959.png 1024w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/a9d273aa85aab5c1736fd66cacfccbad-300x281.png 300w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/a9d273aa85aab5c1736fd66cacfccbad-768x719.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/a9d273aa85aab5c1736fd66cacfccbad.png 1357w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><figcaption id=\"caption-attachment-3304\" class=\"wp-caption-text\">\u91cd\u8907\u907a\u4f1d\u5b50\u306e\u7247\u65b9\u3092\u7834\u58ca\u3057\u305f\u6642\u306b\u4f55\u304c\u8d77\u304d\u308b\u304b\uff1f \u5143\u8ad6\u6587Fig.1\u3092\u6539\u5909\u3002<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001\u51fa\u82bd\u9175\u6bcd\u306e\u91cd\u8907\u907a\u4f1d\u5b5056\u30da\u30a2\u306b\u3064\u3044\u3066\u3053\u308c\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u3044\u3046\u306e\u306f\u7c21\u5358\u3067\u3059\u304c\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u3092\u907a\u4f1d\u5b50\u7834\u58ca\u682a\u3067\u7d44\u7e54\u7684\u306b\u8abf\u3079\u308b\u306e\u306f\u3001\u3051\u3063\u3053\u3046\u5927\u5909\u306a\u5b9f\u9a13\u3067\u3059\u3002\u3053\u306e\u8ad6\u6587\u306e\u4fa1\u5024\u306e\uff11\u3064\u306f\u3001\u300c\u907a\u4f1d\u5b50\u7834\u58ca\u682a\u4e2d\u3067\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u3092\u7d44\u7e54\u7684\u306b\u8abf\u3079\u308b\u300d\u3068\u3044\u3046\u5927\u898f\u6a21\u5b9f\u9a13\u3092\u3084\u3063\u3066\u306e\u3051\u305f\u3053\u3068\u306b\u3042\u308b\u3068\u601d\u3044\u307e\u3059\uff08\u3061\u306a\u307f\u306b\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u306fDHFR\u306e\u5206\u5b50\u76f8\u88dc\u306b\u3088\u308a\u691c\u51fa\u3057\u3066\u3044\u307e\u3059\uff09\u3002<\/p>\n<p>\u7d50\u679c\u3068\u3057\u3066\u300156\u30da\u30a2\u306e\u3046\u306122\u30da\u30a2\u304c\u88dc\u511f\u306e\u95a2\u4fc2\u3092\u6301\u3063\u3066\u3044\u3066\u3001\u305d\u308c\u3068\u540c\u69d8\u306a\u6570\u304c\u4f9d\u5b58\u306e\u95a2\u4fc2\u3092\u6301\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u3042\u3068\u3001\u3053\u306e\u8ad6\u6587\u3067\u306f\u88dc\u511f\u3084\u4f9d\u5b58\u3092\u751f\u307f\u51fa\u3059\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8272\u3005\u3068\u8abf\u3079\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u88dc\u511f\u306f\u91cd\u8907\u30da\u30a2\u3069\u3046\u3057\u306e\u76f8\u624b\u306e\u53d6\u308a\u5408\u3044\u306e\u7d50\u679c\u751f\u3058\u3066\u3044\u308b\u3089\u3057\u3044\u3053\u3068\u3001\u4f9d\u5b58\u306f\u91cd\u8907\u907a\u4f1d\u5b50\u304c\u30b3\u30fc\u30c9\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u540c\u58eb\u304c\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u30db\u30e2\u30de\u30fc\u3092\u4f5c\u308b\u3082\u306e\u306b\u898b\u3089\u308c\u3001\u7247\u65b9\u304c\u58ca\u308c\u308b\u3053\u3068\u3067\u3082\u3046\u4e00\u65b9\u304c\u4e0d\u5b89\u5b9a\u5316\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u751f\u3058\u3066\u3044\u308b\u3089\u3057\u3044\u3053\u3068\uff08\u4e0b\u56f3\uff09\u3001\u306a\u3069\u3067\u3059\u3002<\/p>\n<figure id=\"attachment_3305\" aria-describedby=\"caption-attachment-3305\" style=\"width: 580px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?attachment_id=3305\" rel=\"attachment wp-att-3305\"><img decoding=\"async\" class=\"size-large wp-image-3305\" src=\"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/0fd2e3f2d7d0e70dce5891284df1f8b2-1024x840.png\" alt=\"\" width=\"580\" height=\"476\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/0fd2e3f2d7d0e70dce5891284df1f8b2-1024x840.png 1024w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/0fd2e3f2d7d0e70dce5891284df1f8b2-300x246.png 300w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/0fd2e3f2d7d0e70dce5891284df1f8b2-768x630.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2017\/03\/0fd2e3f2d7d0e70dce5891284df1f8b2.png 1326w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><figcaption id=\"caption-attachment-3305\" class=\"wp-caption-text\">\u4f9d\u5b58\u304c\u8d77\u304d\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3002\u81ea\u5df1\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u30db\u30e2\u30de\u30fc\u306e\u91cd\u8907\u304b\u3089\u751f\u3058\u305f\u30d8\u30c6\u30ed\u30de\u30fc\u304c\u4f9d\u5b58\u3092\u304a\u3053\u3059\u3002\u5143\u8ad6\u6587Fig.4\u3088\u308a\u6539\u5909\u3002<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>\u30bf\u30a4\u30c8\u30eb\u306b\u3082\u306a\u3063\u305f\u672c\u8ad6\u6587\u306e\u300c\u30ad\u30e2\u300d\u306f\u3053\u3053\u3067\u3059\u3002<\/p>\n<p>\u3053\u308c\u307e\u3067\u306e\u901a\u8aac\u3067\u306f\u3001\u907a\u4f1d\u5b50\u91cd\u8907\u306f\u7d30\u80de\u306e\u30b7\u30b9\u30c6\u30e0\u306b\u5197\u9577\u6027\u3092\u751f\u3080\u306a\u3069\u3057\u3066\u300c\u9811\u5065\u6027\uff1aRobustness\uff09\u300d\u3092\u4ed8\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u3067\u306e\u300c\u88dc\u511f\u300d\u306f\u307e\u3055\u306b\u305d\u308c\u306b\u3042\u305f\u308a\u307e\u3059\u3002\u3068\u3053\u308d\u304c\u3001\u300c\u4f9d\u5b58\u300d\u3068\u3044\u3046\u73fe\u8c61\u306b\u3088\u308a\u3001\u91cd\u8907\u3057\u305f\u907a\u4f1d\u5b50\u306e\u30da\u30a2\u306e\u7834\u58ca\u304c\u3082\u3046\u4e00\u65b9\u306e\u6a5f\u80fd\u640d\u5931\u306b\u307e\u3067\u53ca\u3076\u3001\u3064\u307e\u308a<strong>\u907a\u4f1d\u5b50\u91cd\u8907\u306b\u3088\u3063\u3066\u300c\u58ca\u308c\u3084\u3059\u3055\uff08\u8106\u5f31\u6027\uff1aFragility\uff09\u300d\u304c\u5897\u3048\u3066\u3057\u307e\u3046<\/strong>\u3053\u3068\u304c\u3042\u308b\u3001\u3068\u3044\u3046\u306e\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3053\u306e\u8ad6\u6587\u3092\u30d1\u30c3\u3068\u898b\u305f\u3068\u304d\u3001\u79c1\u304c\u6700\u521d\u306b\u601d\u3063\u305f\u306e\u306f\u3001\u300c\u88dc\u511f\u3084\u4f9d\u5b58\u304c\u534a\u3005\u3067\u8d77\u304d\u308b\u3093\u3060\u3063\u305f\u3089\u3001\u907a\u4f1d\u5b50\u91cd\u8907\u306f\u3001\u305d\u3082\u305d\u3082\u907a\u4f1d\u5b50\u7834\u58ca\u306b\u5bfe\u3059\u308b\u7d30\u80de\u30b7\u30b9\u30c6\u30e0\u306e\u9811\u5065\u6027\u306b\u5bfe\u3057\u3066\u4e2d\u7acb\u7684\u3068\u8003\u3048\u308b\u3079\u304d\u3067\u306f\u306a\u3044\u306e\u304b\uff1f\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u305f\u3002<\/p>\n<p>\u907a\u4f1d\u5b50\u91cd\u8907\u306b\u95a2\u3059\u308b\u8457\u540d\u306a\u7814\u7a76\u8005\u3067\u3042\u308b<a href=\"http:\/\/www.the-scientist.com\/?articles.view\/articleNo\/48460\/title\/Duplicated-Genes-May-Reduce-Resilience-in-Yeast\/\" target=\"_blank\" rel=\"noopener\">JianzhiGeorge Zhang\u3084Kenneth Wolfe\u3089\u3082\u3001\u3053\u306e\u8ad6\u6587\u306e\u7d50\u8ad6\u306b\u5bfe\u3057\u3066\u306f\u61d0\u7591\u7684\u306a\u3088\u3046\u3067\u3059<\/a>\u3002\u907a\u4f1d\u5b50\u91cd\u8907\u306b\u3088\u3063\u3066\u3067\u304d\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u3001\u907a\u4f1d\u5b50\u91cd\u8907\u3055\u308c\u3066\u3044\u306a\u3044\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u6bd4\u3079\u3066\u8106\u5f31\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u306e\u304c\uff11\u3064\u306e\u7406\u7531\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u8ad6\u6587\u306e\u6700\u5927\u306e\u767a\u898b\u306f\u3001\u5927\u898f\u6a21\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u76f8\u4e92\u4f5c\u7528\u306e\u89e3\u6790\u3068\u3044\u3046\u3053\u308c\u307e\u3067\u884c\u308f\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u89e3\u6790\u306e\u7d50\u679c\u3001\uff11\u3064\u306e\u5fc5\u9808\u306a\u907a\u4f1d\u5b50\u304b\u3089\uff12\u3064\u306e\u5fc5\u9808\u306a\u907a\u4f1d\u5b50\u304c\u751f\u3058\u308b\u300c\u4f9d\u5b58\u300d\u3068\u3044\u3046\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u898b\u3064\u3051\u305f\u3053\u3068\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u3067\u3059\u304c\u3001\u305d\u308c\u304c\u751f\u547d\u30b7\u30b9\u30c6\u30e0\u306e\u8106\u5f31\u6027\u306e\u767a\u751f\u539f\u7406\u3068\u8a00\u3063\u3066\u826f\u3044\u306e\u304b\u3069\u3046\u304b\u30fb\u30fb\u30fb\u3082\u3046\u5c11\u3057\u8b70\u8ad6\u304c\u5fc5\u8981\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u308c\u304b\u3089\u3001\u3053\u306e\u8ad6\u6587\u3067\u306f\u307b\u3068\u3093\u3069\u907a\u4f1d\u5b50\u540d\u304c\u51fa\u3066\u3053\u306a\u304f\u3066\u3001\u56f3\u306e\u4e2d\u3067\u89e3\u6790\u3055\u308c\u3066\u3044\u308b\u907a\u4f1d\u5b50\u304c\u4f55\u306a\u306e\u304b\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u300c\u5168\u4f53\u306e\u50be\u5411\u3092\u898b\u308b\u306e\u306b\u500b\u5225\u306e\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u306f\u95a2\u4fc2\u306a\u3044\u300d\u3068\u3044\u3046\u59ff\u52e2\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u3069\u306e\u907a\u4f1d\u5b50\u304c\u305d\u3046\u3044\u3046\u632f\u308b\u821e\u3044\u3092\u3057\u3066\u3044\u308b\u306e\u304b\u77e5\u308a\u305f\u3044\u3057\u3001\u907a\u4f1d\u5b50\u540d\u304c\u308f\u304b\u3089\u306a\u3051\u308c\u3070\u8ffd\u8a66\u3082\u3067\u304d\u307e\u305b\u3093\u3002\u3042\u307e\u308a\u826f\u3044\u59ff\u52e2\u3067\u306f\u306a\u3044\u306a\u3068\u601d\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u307e\u305f\u3001\u3053\u306e\u89e3\u6790\u306f\u5b9f\u9a13\u7cfb\u306e\u6027\u8cea\u4e0a\u3001\u975e\u5fc5\u9808\u907a\u4f1d\u5b50\u3057\u304b\u53d6\u308a\u6271\u3048\u307e\u305b\u3093\u3002\u5fc5\u9808\u907a\u4f1d\u5b50\u306e\u65b9\u304c\u7834\u58ca\u306e\u30a4\u30f3\u30d1\u30af\u30c8\u304c\u5927\u304d\u3044\u308f\u3051\u3067\u3059\u3057\u3001<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27708008\" target=\"_blank\" rel=\"noopener\">\u5408\u6210\u81f4\u6b7b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u89e3\u6790\u3067\u3082\u5fc5\u9808\u3068\u975e\u5fc5\u9808\u907a\u4f1d\u5b50\u3067\u306f\u898b\u3048\u3066\u304f\u308b\u3082\u306e\u304c\u9055\u3063\u3066\u3044\u305f<\/a>\u308f\u3051\u3067\u3001\u5fc5\u9808\u907a\u4f1d\u5b50\u3067\u540c\u3058\u3053\u3068\u3092\u3084\u308b\u3068\u7d50\u679c\u3082\u307e\u305f\u9055\u3046\u306e\u304b\u306a\u3068\u601d\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fc\u30fc<\/p>\n<p>\u306a\u304a\u3001\u3053\u306e\u8ad6\u6587\u306f\u907a\u4f1d\u5b50\u91cd\u8907\u306e\u7814\u7a76\u306e\u5c02\u9580\u5bb6\u3067\u3042\u308b\u6771\u5317\u5927\u5b66\u306e\u7267\u91ce\u80fd\u58eb\u3055\u3093\u306b\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u30a8\u30f3\u30c8\u30ea\u30fc\u306e\u57f7\u7b46\u306b\u3042\u305f\u3063\u3066\u3082\u8b70\u8ad6\u30fb\u52a9\u8a00\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u5834\u3092\u501f\u308a\u3066\u304a\u793c\u7533\u3057\u4e0a\u3052\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gene duplicatio&#8230;<\/p>\n","protected":false},"author":3,"featured_media":3305,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[10,11,8,9],"tags":[],"class_list":["post-3301","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-10","category-11","category-8","category-9"],"_links":{"self":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/3301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3301"}],"version-history":[{"count":8,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/3301\/revisions"}],"predecessor-version":[{"id":3422,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/3301\/revisions\/3422"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/media\/3305"}],"wp:attachment":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}