{"id":4325,"date":"2022-11-03T12:46:59","date_gmt":"2022-11-03T03:46:59","guid":{"rendered":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=4325"},"modified":"2022-11-03T12:47:01","modified_gmt":"2022-11-03T03:47:01","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e7%99%ba%e7%8f%be%e9%87%8f%e3%82%92%e6%ad%a3%e7%a2%ba%e3%81%ab%e9%a0%90%e8%a8%80%e3%81%99%e3%82%8bai%e3%81%8c%e7%94%9f%e3%81%be%e3%82%8c%e3%81%9f%ef%bc%882-n%ef%bc%89","status":"publish","type":"post","link":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=4325","title":{"rendered":"\u907a\u4f1d\u5b50\u767a\u73fe\u91cf\u3092\u6b63\u78ba\u306b\u9810\u8a00\u3059\u308bAI\u304c\u751f\u307e\u308c\u305f\uff082\/n\uff09\u30fc\u9810\u8a00\u3092\u691c\u8a3c\u3057\u3066\u307f\u308b"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u306f\u3058\u3081\u306b<\/h2>\n\n\n\n<p>\u524d\u56de\u3001\u300c<a href=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=4293\" title=\"\">\u907a\u4f1d\u5b50\u767a\u73fe\u91cf\uff08\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u5f37\u5ea6\uff09\u3092\u6b63\u78ba\u306b\u4e88\u8a00\u3059\u308bAI\u304c\u751f\u307e\u308c\u305f<\/a>\u300d\u3068\u3044\u3046\u8a71\u3092\u3057\u307e\u3057\u305f\u3002\u4eca\u56de\u306e\u30a8\u30f3\u30c8\u30ea\u30fc\u3067\u306f\u3053\u306eAI\u306e\u9810\u8a00\uff08\u4e88\u8a00\u3088\u308a\u9810\u8a00\u306e\u65b9\u304c\u9069\u5207\u306a\u306e\u3067\u5909\u3048\u307e\u3057\u305f\uff09\u306b\u5f93\u3063\u3066\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u9032\u5316\u3055\u305b\u3066\u307f\u305f\u3068\u3044\u3046\u8a71\u3092\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306eAI\u3092\u4f5c\u3063\u305fMIT\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30a6\u30a7\u30d6\u4e0a\u3067\u3053\u306eAI\u3092\u4f7f\u3046\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046<a href=\"https:\/\/1edv-evolution-appapp-6gj665.streamlitapp.com\/\" title=\"\">API*\u3092\u516c\u958b\u3057\u3066\u304f\u308c\u3066\u3044\u307e\u3059<\/a>\u3002\u4eba\u985e\u306e\u9032\u6b69\u306e\u305f\u3081\u306a\u3089\u3001\u81ea\u5206\u9054\u304c\u4f5c\u3063\u305f\u3082\u306e\u3092\u8ab0\u3067\u3082\u4f7f\u3048\u308b\u3088\u3046\u306b\u3001\u72ec\u5360\u305b\u305a\u6f54\u304f\u516c\u958b\u3059\u308b\u30a2\u30ab\u30c7\u30df\u30a2\u306e\u7d20\u6674\u3089\u3057\u3055\u30fb\u30ab\u30c3\u30b3\u3088\u3055\u3092\u611f\u3058\u307e\u3059\u3002\u307e\u3042\u3001\u516c\u958b\u3059\u308b\u524d\u306b\u7f8e\u5473\u3057\u3044\u3068\u3053\u308d\u306f\u81ea\u5206\u9054\u3067\u5341\u5206\u306b\u304a\u3055\u3048\u3066\u3044\u308b\u3057\u3001\u305d\u3046\u7c21\u5358\u306b\u8ffd\u3044\u3064\u304b\u308c\u308b\u3053\u3068\u3082\u306a\u3044\u3068\u3044\u3046\u4f59\u88d5\u306e\u306a\u305b\u308b\u6280\u3067\u3082\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u3055\u3066\u3001\u3053\u306eAPI\u3092\u4f7f\u3046\u3068\u3001AI\u306e\u9810\u8a00\u306b\u57fa\u3065\u3044\u3066\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u9032\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3068\u3044\u3046\u308f\u3051\u3067\u3001\u65e9\u901f\u3084\u3063\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002\uff65\uff65\uff65\u305d\u306e\u524d\u306b\u3001\u307e\u305a\u306f\u4eca\u56de\u9032\u5316\u3055\u305b\u3088\u3046\u3068\u3059\u308b\u9175\u6bcd\u306eTDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306b\u3064\u3044\u3066\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u6700\u5f37TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc<\/h2>\n\n\n\n<p>TDH3\u306f\u9175\u6bcd\u306e\u4e2d\u3067\u3082\u3063\u3068\u3082\u305f\u304f\u3055\u3093\u767a\u73fe\u3057\u3066\u3044\u308b\u907a\u4f1d\u5b50\u3067\u3001\u305d\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306f\u6700\u5f37\u306e\uff11\u3064\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/yea.1806\" title=\"\">Partow 2010<\/a>\uff09\u3002\u79c1\u306f\u305d\u306e\u300c\u6700\u5f37\u3055\u300d\u306b\u60da\u308c\u8fbc\u3093\u3067\u3001\u9175\u6bcd\u3067\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u305f\u304f\u3055\u3093\u4f5c\u3089\u305b\u308b\u305f\u3081\u306b\u3053\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u4f7f\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u69cb\u9020\u306f\u56f3\uff11\u306e\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-style-rounded\"><a href=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2.png\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"390\" src=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-1024x390.png\" alt=\"\" class=\"wp-image-4328\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-1024x390.png 1024w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-300x114.png 300w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-768x293.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-1536x585.png 1536w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-2048x781.png 2048w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-2-956x364.png 956w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption>\u56f3\uff11. TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u69cb\u9020\uff08<a href=\"https:\/\/elifesciences.org\/articles\/69549\" title=\"\">Azizoglu 2021<\/a>, <a href=\"https:\/\/www.nature.com\/articles\/nature07667\" title=\"\">Kaplan 2009<\/a>\u306a\u3069\u53c2\u7167\uff09<\/figcaption><\/figure>\n\n\n\n<p>\u3053\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u6700\u5f37\u306e\u8ee2\u5199\u306f\u3001\u8ee2\u5199\u5236\u5fa1\u56e0\u5b50\uff08Rap1, Gcr1\uff09\u304c\u7d50\u5408\u3059\u308b\u9818\u57df\uff08 \u2460 \u2013514\u301c\u2013288 from ATG\uff09\u306b\u3088\u3063\u3066\u5b9f\u73fe\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u9818\u57df\u2460\u306fTDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u5fc3\u81d3\u90e8\u3068\u3082\u3044\u3048\u307e\u3059\u3002\u4e00\u65b9\u3001AI\u306e\u5b66\u7fd2\u3067\u3082\u3061\u3044\u3089\u308c\u305f\u306e\u306f\u3001TSS\u306e\u4e0a\u6d41\u57df\uff08\u2461 \u2013170\u301c\u201390 from TSS\uff09\u306e80bp\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u3053\u3067\u4eca\u56de\u306f\u3001\u3053\u306e\uff12\u3064\u306e\u9818\u57df\u3092AI\u3067\u8a55\u4fa1\u3057\u3066\u9032\u5316\u3055\u305b\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">AI\u306e\u9810\u8a00\u306b\u3057\u305f\u304c\u3063\u3066TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u9032\u5316\u3055\u305b\u308b<\/h2>\n\n\n\n<p>\u4e0a\u8a18\u306eAPI\u3067\u307e\u305a\u306f\u2460\u306e\u914d\u5217\u3092\u89e3\u6790\u3057\u3066\u307f\u307e\u3059\u3002\u3053\u3053\u306fTDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u5fc3\u81d3\u90e8\u3067\u3059\u304c\u3001AI\u306e\u5b66\u7fd2\u306b\u3082\u3061\u3044\u3089\u308c\u305f\u9818\u57df\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5f93\u3063\u3066\u3001AI\u306e\u9810\u8a00\u304c\u3069\u308c\u304f\u3089\u3044\u6c4e\u7528\u6027\u304c\u3042\u308b\u304b\u3092\u77e5\u308b\u306b\u306f\u826f\u3044\u6750\u6599\u3060\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9.png\"><img decoding=\"async\" width=\"1024\" height=\"530\" src=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-1024x530.png\" alt=\"\" class=\"wp-image-4336\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-1024x530.png 1024w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-300x155.png 300w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-768x398.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-1536x795.png 1536w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-2048x1060.png 2048w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-9-956x495.png 956w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption>\u56f3\uff12. TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u9818\u57df\u2460\u306eAI\u9810\u8a00\u306b\u57fa\u3065\u304f\u9032\u5316\u3002\u9032\u5316\u524d\u306e\u914d\u5217\u3092AI\u306b\u8aad\u307f\u8fbc\u307e\u305b\u308b\u3068\u3001\u3069\u306e\u5869\u57fa\u3092\u5909\u5316\u3055\u305b\u308b\u3068\u767a\u73fe\u5f37\u5ea6\u304c\u3082\u3063\u3068\u3082\u4e0a\u304c\u308b\u304b\uff08\u5b9f\u7dda\u56db\u89d2\uff09\u3001\u3082\u3063\u3068\u3082\u4e0b\u304c\u308b\u304b\uff08\u70b9\u7dda\u56db\u89d2\uff09\u3092\u6559\u3048\u3066\u304f\u308c\u308b\u3002\u56db\u89d2\u3092\u30af\u30ea\u30c3\u30af\u3059\u308b\u3068\u3001\u5869\u57fa\u3092\u7f6e\u63db\u3057\u305f\u3042\u3068\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306b\u5bfe\u3057\u3066\u540c\u3058\u89e3\u6790\u304c\u306a\u3055\u308c\u3001\u307e\u305f\u3069\u3053\u3092\u5909\u5316\u3055\u305b\u305f\u3089\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u6d3b\u6027\u304c\u5909\u5316\u3059\u308b\u304b\u3092\u9810\u8a00\u3057\u3066\u304f\u308c\u308b\u3002\u3053\u308c\u3092\u7e70\u308a\u8fd4\u3059\u3068\u3001\u4e0e\u3048\u3089\u308c\u305f\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u304c\u6700\u5f37\uff0f\u6700\u5f31\u3078\u3068\u9032\u5316\u3059\u308b\u3002\u8ee2\u5199\u56e0\u5b50\u306e\u7d50\u5408\u90e8\u4f4d\u306e\u63a2\u7d22\u306f<a href=\"http:\/\/yetfasco.ccbr.utoronto.ca\/\" title=\"\">YeTFaSco<\/a>\u3067\u884c\u3063\u305f\u3002\u6700\u5f37\u9032\u5316\u5f8c\uff08Evo1\uff09\u306b\u95a2\u3057\u3066\u56f3\uff14\u306e\u5b9f\u9a13\u3067\u767a\u73fe\u91cf\u3092\u8abf\u67fb\u3057\u305f\u3002<\/figcaption><\/figure>\n\n\n\n<p>\u56f3\uff12\u306e\u3088\u3046\u306b\u300180bp\u306e\u914d\u5217\u3092\u5165\u529b\u3059\u308b\u3068\u305d\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u767a\u73fe\u5f37\u5ea6\u304c\u4e88\u6e2c\u3055\u308c\u3001\u3055\u3089\u306b\u3069\u306e\u5869\u57fa\u3092\u3069\u3046\u7f6e\u63db\u3057\u305f\u3089\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u6d3b\u6027\u304c\u4e0a\u304c\u308b\u304b\u4e0b\u304c\u308b\u304b\u3092\u6559\u3048\u3066\u304f\u308c\u307e\u3059\uff08\u305d\u308c\u4ee5\u5916\u306e\u3044\u308d\u3093\u306a\u6a5f\u80fd\u3082\u3053\u306eAPI\u306b\u306f\u3042\u308a\u307e\u3059\uff09\u3002\u6700\u5f37TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u9818\u57df\u2460\u306e\u767a\u73fe\u91cf\u306f14.0\u3067\u3001\u300c\u308f\u308a\u3068\u5f37\u3044\u300d\u90e8\u985e\u306b\u5165\u308b\u3068\u9810\u8a00\u3055\u308c\u307e\u3057\u305f\u3002\u3067\u3059\u304cAI\u306f\u300c\u3053\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306f\u3082\u3063\u3068\u5f37\u304f\u306a\u308b\u300d\u3068\u8a00\u3046\u306e\u3067\u3001\u305d\u308c\u306b\u5f93\u3063\u3066\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u3092\u9032\u5316\u3055\u305b\u3066\u307f\u307e\u3057\u305f\uff08\u8a73\u7d30\u306f\u56f3\uff12\u306e\u30ad\u30e3\u30d7\u30b7\u30e7\u30f3\uff09\u3002\u7d50\u679c\u3068\u3057\u3066\u300129\u30ab\u6240\u3092\u7f6e\u63db\u3057\u3066\u3067\u304d\u305f\u914d\u5217\u306f\u767a\u73fe\u91cf22.0\u3001\u9032\u5316\u524d\u306e1.6\u500d\u306e\u767a\u73fe\u91cf\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u9032\u5316\u5f8c\u306e\u914d\u5217\u3067\u306f\u3082\u3068\u3082\u3068TDH3\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u6d3b\u6027\u306b\u5fc5\u8981\u3060\u3063\u305fGcr1\u306e\u7d50\u5408\u914d\u5217\u306f\u306a\u304f\u306a\u308a\u307e\u3057\u305f\u304c\u3001Rap1\u306e\u7d50\u5408\u914d\u5217\u306f\u6b8b\u308a\u3001\u307e\u305f\u3082\u3068\u3082\u3068\u3042\u3063\u305fRap1\u306e\u7d50\u5408\u90e8\u4f4d\u3092\u89e6\u308b\u3068\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306f\u5f31\u304f\u306a\u308b\u3068\u9810\u8a00\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u3053\u306eAI\u306f\uff08\u5b66\u7fd2\u30c7\u30fc\u30bf\u306b\u306f\u7528\u3044\u3066\u3044\u306a\u3044\uff09Rap1\u306e\u7d50\u5408\u914d\u5217\u304c\u8ee2\u5199\u6d3b\u6027\u5316\u306b\u5fc5\u8981\u3060\u3068\u3044\u3046\u3053\u3068\u3092\uff08\u81ea\u5206\u3067\u5b66\u3093\u3067\uff09\u5185\u90e8\u60c5\u5831\u3068\u3057\u3066\u6301\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8.png\"><img decoding=\"async\" width=\"1024\" height=\"584\" src=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-1024x584.png\" alt=\"\" class=\"wp-image-4335\" srcset=\"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-1024x584.png 1024w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-300x171.png 300w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-768x438.png 768w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-1536x877.png 1536w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-2048x1169.png 2048w, https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/wp-content\/uploads\/2022\/11\/image-8-956x546.png 956w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption>\u56f33. 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