{"id":59,"date":"2010-04-15T18:14:52","date_gmt":"2010-04-15T09:14:52","guid":{"rendered":"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=59"},"modified":"2010-04-15T18:14:52","modified_gmt":"2010-04-15T09:14:52","slug":"metabolic-cycling-in-single-yeast-cells-from-unsynchronized-steady-state-populations-limited-on-glucose-or-phosphate","status":"publish","type":"post","link":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=59","title":{"rendered":"Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate."},"content":{"rendered":"<div class=\"section\">\n<blockquote>\n<p>Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D.<\/p>\n<p>Proc Natl Acad Sci U S A. 2010 Mar 24. [Epub ahead of print]PMID: 20335538<\/p>\n<\/blockquote>\n<p>\u6065\u305a\u304b\u3057\u306a\u304c\u3089\u3001\u3053\u306e\u8ad6\u6587\u3092\u8aad\u3093\u3067\u59cb\u3081\u3066\u300c\u305d\u3046\u304b\uff01\u300d\u3068\u6c17\u3065\u3044\u305f\u306e\u3060\u304c\u3001\u7d30\u80de\u5185\u306e\u4ee3\u8b1d\u306f\u3001&#8221;Metabolic Incompatibility&#8221;\uff08\u4ee3\u8b1d\u4e0d\u548c\u5408\u6027\uff09\u306e\u30b8\u30ec\u30f3\u30de\u3092\u5e38\u306b\u6301\u3063\u3066\u3044\u308b\u3002\u4f8b\u3048\u3070\u3001\u6700\u3082\u5206\u304b\u308a\u3084\u3059\u3044\u4f8b\u3067\u306f\u3001ATP\u306f\u7d30\u80de\u5185\u3067\u4f5c\u3089\u308c\u306a\u304c\u3089\u6d88\u8cbb\u3082\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u306e\u4e21\u8005\u306e\u53cd\u5fdc\u304c\u307e\u3068\u3082\u306b\u52d5\u304f\u305f\u3081\u306b\u306f\u3001\u5f53\u7136\u4f55\u3089\u304b\u306e\u65b9\u6cd5\u30672\u3064\u306e\u53cd\u5fdc\u304c\u8d77\u3053\u308b\u300c\u5834\u300d\u3092\u9694\u3066\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n<p>\u7d30\u80de\u5185\u306e\u819c\u69cb\u9020\u306f\u3001\u3053\u306e\u305f\u3081\u306b\u3057\u3070\u3057\u3070\u7528\u3044\u3089\u308c\u308b\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3084\u8449\u7dd1\u4f53\u7b49\u306f\u305d\u306e\u6700\u305f\u308b\u4f8b\u3067\u3042\u308d\u3046\u3002<\/p>\n<p>\u4e00\u65b9\u3067\u3001\u7d30\u80de\u306f\u3001Metabolic Oscillation\uff08\u4ee3\u8b1d\u632f\u52d5\uff09\u3068\u3044\u3046\u73fe\u8c61\u306b\u3088\u3063\u3066\u3001\u4ee3\u8b1d\u7cfb\u3092\u6642\u9593\u306b\u3088\u3063\u3066\u9023\u7d9a\u7684\u306b\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u4ee3\u8b1d\u4e0d\u548c\u5408\u6027\u3092\u3055\u3051\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u306f\u3001\u7279\u306b\u9175\u6bcd\u7d30\u80de\u3067\u306f\u3001\u30b1\u30e2\u30b9\u30bf\u30c3\u30c8\u3068\u547c\u3070\u308c\u308b\u9023\u7d9a\u57f9\u990a\u7cfb\u3067\u3001\u7d30\u80de\u304c\u7279\u5b9a\u306e\u5bc6\u5ea6\u4ee5\u4e0a\u306b\u306a\u3063\u305f\u6642\u306b\u89b3\u5bdf\u3055\u308c\u308b\u3002\u3053\u306e\u4ee3\u8b1d\u632f\u52d5\u3067\u306f\u3001\u975e\u5e38\u306b\u591a\u304f\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5468\u671f\u7684\u306b\u5909\u5316\u3059\u308b\u3002\u3053\u306e\u4ee3\u8b1d\u632f\u52d5\u306f\u3001\u7d30\u80de\u306b\u672c\u6765\u5099\u308f\u3063\u3066\u3044\u308b\u300c\u6642\u8a08\u300d\u306a\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u5358\u306a\u308b\u74b0\u5883\u3078\u306e\u9069\u5fdc\u304c\u7e70\u308a\u8fd4\u3055\u308c\u308b\u3053\u3068\u3067\u304a\u304d\u308b\u540c\u8abf\u30fb\u632f\u52d5\u306a\u306e\u304b\u306f\u3001\u306f\u3063\u304d\u308a\u3068\u3057\u305f\u7d50\u8ad6\u304c\u51fa\u3066\u3044\u306a\u304b\u3063\u305f\uff08\u79c1\u306f\u5f8c\u8005\u3060\u3068\u601d\u3063\u3066\u3044\u305f\uff09\u3002<\/p>\n<p>\u9175\u6bcd\u7814\u7a76\u306e\u5927\u5fa1\u6240\u3001Botstein\u6c0f\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u767a\u8868\u3055\u308c\u305f\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001FISH\u3092\u7528\u3044\u3066\uff11\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u8ee2\u5199\u7523\u7269\u3092\u691c\u51fa\u3057\u305f\u3068\u3053\u308d\u3001\u4ee3\u8b1d\u4e0d\u548c\u5408\u6027\u3092\u3055\u3051\u308b\u305f\u3081\u306b\u305d\u308c\u305e\u308c\u306e\u907a\u4f1d\u5b50\u304c\u5468\u671f\u7684\u306a\u5909\u52d5\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u8a3c\u62e0\u304c\u5f97\u3089\u308c\u305f\u3002\u3055\u3089\u306b\u3001\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u3053\u306e\u5468\u671f\u5909\u52d5\u306f\u3001\u30b1\u30e2\u30b9\u30bf\u30c3\u30c8\u306b\u3088\u3063\u3066\u540c\u8abf\u3055\u308c\u3066\u3044\u306a\u3044\u57f9\u990a\u7cfb\u306e\u3001\u304a\u306e\u304a\u306e\u306e\u7d30\u80de\u3067\u500b\u5225\u306b\u304a\u304d\u3066\u3044\u305f\u3002<\/p>\n<p>\u3064\u307e\u308a\u3001\u4ee3\u8b1d\u632f\u52d5\u306f\u3001\u7d30\u80de\u306b\u672c\u6765\u5099\u308f\u3063\u3066\u3044\u308b\u6642\u8a08\u306a\u306e\u3060\u3002<\/p>\n<p>\u3053\u306e\u632f\u52d5\u304c\u3069\u306e\u3088\u3046\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u304a\u304d\u3066\u3044\u308b\u306e\u304b\u3001\u7d30\u80de\u5468\u671f\u306e\u3088\u3046\u306a\u5225\u306e\u632f\u52d5\u7cfb\u3068\u3069\u306e\u3088\u3046\u306a\u95a2\u4fc2\u306b\u3042\u308b\u306e\u304b\u30fb\u30fb\u30fb\u4eca\u5f8c\u306e\u89e3\u6790\u304c\u5f85\u305f\u308c\u308b\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Silverman SJ, P&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[10,9],"tags":[],"class_list":["post-59","post","type-post","status-publish","format-standard","hentry","category-10","category-9"],"_links":{"self":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/59","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=59"}],"version-history":[{"count":0,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/59\/revisions"}],"wp:attachment":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=59"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=59"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=59"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}