{"id":80,"date":"2011-04-10T00:00:00","date_gmt":"2011-04-09T15:00:00","guid":{"rendered":"http:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=80"},"modified":"2011-04-28T17:14:02","modified_gmt":"2011-04-28T08:14:02","slug":"%e3%82%a2%e3%83%b3%e3%83%81%e3%82%bb%e3%83%b3%e3%82%b9%e3%81%aa%e7%99%ba%e7%8f%be%e3%81%af%e3%80%81%e9%81%ba%e4%bc%9d%e5%ad%90%e7%99%ba%e7%8f%be%e3%81%ae%e3%81%b0%e3%82%89%e3%81%a4%e3%81%8d%e3%81%a8","status":"publish","type":"post","link":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/?p=80","title":{"rendered":"\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u306a\u767a\u73fe\u306f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u3070\u3089\u3064\u304d\u3068\u907a\u4f1d\u5b50\u30ed\u30fc\u30ab\u30b9\u306e\u76f8\u4e92\u4f9d\u5b58\u6027\u3092\u5897\u52a0\u3055\u305b\u308b\u3002"},"content":{"rendered":"<div class=\"section\">\n<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=21326235\">Antisense expression increases gene expression variability and locus interdependency.<\/a><\/p>\n<p>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b5\u30fc\u3068\u30bf\u30a4\u30ea\u30f3\u30b0\u30a2\u30ec\u30a4\u306e\u529b\u3067\u3001\u9175\u6bcd\uff08<em>S. cerevisiae<\/em>\uff09\u3067\u306f\u3001\u30b2\u30ce\u30e0\u4e0a\u306e\u3069\u3053\u304b\u3089RNA\u304c\u8ee2\u5199\u3055\u308c\u3066\u3044\u308b\u304b\u304c\u7cbe\u5bc6\u306b\u5206\u304b\u3063\u3066\u304d\u3066\u3044\u308b\u3002<\/p>\n<p>\u305d\u3053\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u4e8b\u306f\u3001\u9175\u6bcd\u306e\u30b2\u30ce\u30e0\u4e0a\u306b\u6ca2\u5c71\u306e\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u306a\u8ee2\u5199\uff08ORF\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u306a\u3044\u8ee2\u5199\uff09\u304c\u304a\u304d\u3066\u3044\u308b\u4e8b\u3067\u3042\u308b\u3002\u672c\u8ad6\u6587\u3067\u306f\u3001\u4e00\u5272\u7a0b\u5ea6\u306e\u907a\u4f1d\u5b50\u304c\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9RNA\u3092\u6301\u3063\u3066\u3044\u308b\u3068\u8ff0\u3079\u3066\u3044\u308b\u3002<\/p>\n<p>\u554f\u984c\u306f\u3001\u300c\u3053\u306e\u3088\u3046\u306a\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u306a\u8ee2\u5199\u304c\u751f\u7406\u5b66\u7684\u306a\u6a5f\u80fd\u3092\u6301\u3063\u3066\u3044\u308b\u306e\u304b\uff1f\u300d\u3067\u3042\u308d\u3046\u3002<\/p>\n<p>\u672c\u8ad6\u6587\u3067\u306f\u3001\u30bb\u30f3\u30b9\u306e\u8ee2\u5199\u3068\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u306e\u8ee2\u5199\u304c\u304a\u4e92\u3044\u306b\u62ee\u6297\u3059\u308b\u4e8b\u3067\u30b9\u30a4\u30c3\u30c1\u3092\u5f62\u6210\u3059\u308b\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u8ff0\u3079\u3066\u3044\u308b\u3002<\/p>\n<p>\u5177\u4f53\u7684\u306a\u4f8b\u3068\u3057\u3066\u3001<em>FUR4<\/em>\u907a\u4f1d\u5b50\u5ea7\u3092\u3042\u3052\u3001FUR4\u907a\u4f1d\u5b50\u304c\u6291\u5236\u72b6\u614b\u306b\u3042\u308b\u6642\uff08\u30d5\u30a7\u30ed\u30e2\u30f3\u304c\u306a\u3044\u3068\u304d\uff09\u3001\u304b\u3064\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u8ee2\u5199\u304c\u8a98\u5c0e\u3055\u308c\u308b\u6761\u4ef6\uff08\u30ac\u30e9\u30af\u30c8\u30fc\u30b9\u57f9\u5730\uff09\u306b\u304a\u3044\u3066\u3001<em>FUR4<\/em>\u907a\u4f1d\u5b50\u306e\u6291\u5236\u304c\u3088\u308a\u5f37\u304f\u306a\u308b\u4e8b\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n<p>\u5b9f\u969b\u306b\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u8ee2\u5199\u304c\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5236\u5fa1\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u4f8b\u306f\u3044\u304f\u3064\u304b\u5831\u544a\u3055\u308c\u3066\u3044\u308b\uff08\u4f8b\u3048\u3070\u4ee5\u4e0b\uff09\u3002<\/p>\n<p>Nutrient-regulated antisense and intragenic RNAs modulate a signal transduction pathway in yeast.<br \/>\nPLoS Biol. 2008 Dec 23;6(12):2817-30.<br \/>\nNishizawa M, Komai T, Katou Y, Shirahige K, Ito T, Toh-E A.<\/p>\n<p>\u305f\u3060\u3001\u305d\u308c\u304c\u4e00\u822c\u7684\u306b\u3001\u304b\u3064\u3069\u308c\u304f\u3089\u3044\u306e\u91cd\u8981\u5ea6\u3092\u3082\u3063\u3066\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u306e\u304b\u3001\u79c1\u306f\u591a\u5c11\u61d0\u7591\u7684\u3067\u3042\u308b\u3002<\/p>\n<p>\u4f8b\u3048\u3070\u3001<em>FUR4<\/em>\u306e\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u306e\u767a\u73fe\u306f\u30ac\u30e9\u30af\u30c8\u30fc\u30b9\u3067\u8a98\u5c0e\u3055\u308c\u308b\u304c\u3001\u305d\u308c\u306f<em>FUR4<\/em>\u306e\u4e0b\u6d41\u306b\u3042\u308b\u907a\u4f1d\u5b50<em>GAL80<\/em>\u3092\u30ac\u30e9\u30af\u30c8\u30fc\u30b9\u3067\u8a98\u5c0e\u3057\u305f\u3044\u304c\u305f\u3081\u306b\u3001\u8aa4\u3063\u3066\u304a\u304d\u3066\u3044\u308b\u8ee2\u5199\u306e\u30ce\u30a4\u30ba\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u305d\u306e\u30ce\u30a4\u30ba\u304c\u305f\u307e\u305f\u307e<em>FUR4<\/em>\u306e\u8ee2\u5199\u306b\u5f71\u97ff\u3092\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u3066\u3044\u308b\u3060\u3051\u306a\u306e\u3067\u306f\u306a\u3044\u304b\uff1f<\/p>\n<p>\u300c\u305d\u3046\u3044\u3046\u6a5f\u69cb\u304c\u3042\u308a\u3046\u308b\u300d\u3068\u3044\u3046\u4f8b\u3068\u3057\u3066\u8a8d\u8b58\u306f\u3057\u3066\u304a\u304f\u306e\u306f\u3044\u3044\u3068\u601d\u3046\u304c\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Antisense expre&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[8,9],"tags":[],"class_list":["post-80","post","type-post","status-publish","format-standard","hentry","category-8","category-9"],"_links":{"self":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/80","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=80"}],"version-history":[{"count":3,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/80\/revisions"}],"predecessor-version":[{"id":101,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=\/wp\/v2\/posts\/80\/revisions\/101"}],"wp:attachment":[{"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=80"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=80"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tenure5.vbl.okayama-u.ac.jp\/HM_blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=80"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}