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\"\"<\/a>

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\u3053\u308c\u306f\u5b88\u5c4b\u306b\u3068\u3063\u3066\u304b\u306a\u308a\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc\u306e\u304b\u304b\u308b\u3082\u306e\u3060\u3063\u305f\u3002\u5f53\u6642\u306e\u5b88\u5c4b\u7814\u306e\u898f\u6a21\u306f\u5c0f\u3055\u304f\u3001\u3053\u306e\u9818\u57df\u7814\u7a76\u3092\u30ac\u30f3\u30ac\u30f3\u63a8\u9032\u3067\u304d\u308b\u4eba\u3082\u3044\u306a\u304b\u3063\u305f\u3002\u5c11\u306a\u304f\u3068\u3082\u5165\u308c\u304b\u3048\u6226\u306b\u52dd\u305f\u306a\u3044\u3068\u6b21\u304c\u306a\u3044\u3002\u7d50\u5c40\u5206\u304b\u3063\u305f\u3053\u3068\u306f\u3001\u300c\u3046\u307e\u3044\u3053\u3068\u3084\u308b\u300d\u3053\u3068\u3002\u306f\u3058\u3081\u306e\u8a08\u753b\u3084\u304a\u984c\u76ee\u304b\u3089\u306f\u82e5\u5e72\u305a\u308c\u305f\u3068\u3057\u3066\u3082\u3001\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u3066\u9762\u767d\u3044\u6210\u679c\u304c\u51fa\u3066\u3044\u308c\u3070\u3001\u305d\u308c\u3067\u826f\u3044\u3068\u3044\u3046\u3053\u3068\u3060\u3063\u305f\u3002\u3060\u304c\u3001\u305d\u308c\u3092\u5b66\u3076\u306b\u306f\u3057\u3070\u3089\u304f\u304b\u304b\u308b\u3002\u307e\u3055\u306b\u5b88\u5c4b\u7814\u306e\u8ff7\u8d70\u3092\u8c61\u5fb4\u3059\u308b\u306e\u304c\u3053\u306e\u907a\u4f1d\u60c5\u5831\u5834\u306e\u7814\u7a76\u3060\u3063\u305f\u3002\u3053\u306e\u7814\u7a76\u306e\u76f4\u63a5\u306e\u6210\u679c\u306fPLoS One\u306b\u63b2\u8f09\u3055\u308c\u305f\u3002\u5206\u88c2\u9175\u6bcd\u306e\u7d30\u80de\u5468\u671f\u5236\u5fa1\u3067\u907a\u4f1d\u5b50\u91cf\u88dc\u511f\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u8ad6\u6587\u306b\u306a\u308b\uff08Chino PLoS One 2013<\/a>\uff09\u3002\u5f53\u521d\u306e\u8a08\u753b\u307b\u3069\u3046\u307e\u304f\u884c\u304b\u306a\u304b\u3063\u305f\u304c\u3001\u3053\u3053\u3067\u306e\u5b9f\u9a13\u306e\u30a2\u30a4\u30c7\u30a2\u3084\u7d4c\u9a13\u306f\u3001\u3053\u306e\u5f8c\u3001\u3053\u306e\u30c6\u30fc\u30de\u306f\u91cf\u88dc\u511f\u306e\u30c6\u30fc\u30de\u3068\u3057\u3066\u82b1\u958b\u304f\u3002<\/p>\n\n\n\n

\"\"<\/a>
\u5206\u88c2\u9175\u6bcd\u3067gTOW\u306b\u3088\u308a\u91cf\u88dc\u511f\u3092\u8abf\u3079\u308b\u5b9f\u9a13\u3002Chino 2013\u3088\u308a<\/figcaption><\/figure>\n\n\n\n

\u3061\u306a\u307f\u306b\u3001\u3053\u306e\u907a\u4f1d\u60c5\u5831\u5834\u306e\u9818\u57df\u4f1a\u8b70\u3067\u306f\u3001\u5b88\u5c4b\u306e\u4ed5\u4e8b\u3092\u300c\u30ed\u30c3\u30af\u3060\u300d\u3068\u9ad8\u8a55\u4fa1\uff08\uff1f\uff09\u3057\u3066\u304f\u308c\u305f\u65b9\u304c\u3044\u305f\u3002\u305d\u306e\u5f53\u6642\u3042\u307e\u308a\u30d4\u30f3\u3068\u304d\u3066\u306a\u304b\u3063\u305f\u304c\u3001\u4eca\u306f\u306a\u3093\u3068\u306a\u304f\u3001\u300c\u30ed\u30c3\u30af\u306a\u3093\u304b\u306a\uff1f\u300d\u3068\u306f\u601d\u3044\u59cb\u3081\u3066\u3044\u308b\u3002\u306a\u304a\u3001\u3053\u306e\u6642\u306e\u7814\u7a76\u8ab2\u984c\u306f\u4ee5\u4e0b\u306e\uff12\u3064\u3067\u3042\u308b\u3002<\/p>\n\n\n\n

    \n
  1. \u907a\u4f1d\u60c5\u5831\u5834\u3078\u306e\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u306e\u540c\u5b9a<\/a>\uff082009-2010\uff09<\/li>\n\n\n\n
  2. \u60c5\u5831\u5834\u3078\u306e\u6442\u52d5\u3092\u7de9\u885d\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/a>\uff082011-2012\uff09<\/li>\n<\/ol>\n\n\n\n

    \u79d1\u7814\u8cbb\u30fb\u57fa\u76e4B\u30c6\u30fc\u30de<\/h2>\n\n\n\n

    \u79d1\u7814\u8cbb\u306e\u4e2d\u6838\u3092\u306a\u3059\u306e\u306f\u300c\u57fa\u76e4\u7814\u7a76\u300d\u3068\u3044\u3046\u30ab\u30c6\u30b4\u30ea\u30fc\u3067\u3042\u308b\u3002\u65b0\u5b66\u8853\u9818\u57df\u306a\u3069\u306e\u304a\u984c\u76ee\u304c\u6c7a\u307e\u3063\u3066\u3044\u308b\u7814\u7a76\u8cbb\u3068\u9055\u3044\u3001\u57fa\u76e4\u7814\u7a76\u3067\u306f\u7814\u7a76\u8005\u306e\u81ea\u7531\u306a\u767a\u60f3\u306b\u3088\u308b\u7814\u7a76\u3092\u304a\u3053\u306a\u3046\u3002\u3064\u307e\u308a\u3001\u81ea\u5206\u304c\u3084\u308a\u305f\u3044\u3053\u3068\u3092\u30b9\u30c8\u30ec\u30fc\u30c8\u306b\u62bc\u3057\u51fa\u3057\u3066\u7533\u8acb\u66f8\u3092\u66f8\u3051\u3070\u826f\u3044\u3002\u4e00\u65b9\u3001\u304a\u984c\u76ee\u304c\u306a\u3044\u5206\u3001\u3084\u308a\u305f\u3044\u3053\u3068\u304c\u3069\u308c\u3060\u3051\u5b66\u8853\u7684\u306b\u610f\u7fa9\u304c\u3042\u308b\u304b\u3092\u8aac\u304b\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002\u5b88\u5c4b\u306f2011\u5e74\u304b\u3089\u305a\uff15\u56de\u3064\u3065\u3051\u3066\u57fa\u76e4B\u306b\u63a1\u629e\u3055\u308c\u7d9a\u3051\u3066\u3044\u308b\u3002\u57fa\u76e4B\u3053\u305d\u304c\u30b9\u30c8\u30ec\u30fc\u30c8\u306b\u305d\u306e\u6642\u306egTOW\u306e\u30e1\u30a4\u30f3\u30c6\u30fc\u30de\u3092\u8868\u3057\u3066\u3044\u308b\u3068\u8a00\u3063\u3066\u3082\u3044\u3044\u3002\u3061\u306a\u307f\u306b\u3001\u5b88\u5c4b\u304c\u63a1\u629e\u3055\u308c\u305f\u3053\u3068\u304c\u3042\u308b\u57fa\u76e4B\u4ee5\u5916\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u306b\u3001\u9818\u57df\u7814\u7a76\u306e\u516c\u52df\u3068\u6311\u6226\u7684\u840c\u82bd\u304c\u3042\u308b\u3002\u524d\u8005\u306f\u4e0a\u8ff0\u3057\u305f\u3088\u3046\u306a\u304a\u984c\u76ee\u306b\u6cbf\u3063\u305f\u79d1\u7814\u8cbb\u30ab\u30c6\u30b4\u30ea\u30fc\u3067\u3001\u6311\u6226\u7684\u840c\u82bd\u306f\u57fa\u76e4\u3088\u308a\u3082\u65ac\u65b0\u306a\u30c6\u30fc\u30de\u304c\u6c42\u3081\u3089\u308c\u308b\u3002\u3053\u308c\u3089\u306b\u3064\u3044\u3066\u306f\u307e\u305f\u5225\u3067\u8ff0\u3079\u308b\u3068\u3057\u3066\u3001\u57fa\u76e4B\u306e\u30bf\u30a4\u30c8\u30eb\u3092\u898b\u3066\u5b88\u5c4b\u7814\u306e\u7814\u7a76\u306e\u5909\u9077\u3092\u898b\u3066\u307f\u3088\u3046\u3002<\/p>\n\n\n\n

      \n
    1. \u9175\u6bcd\u306e\u91cf\u7684\u5747\u8861\u907a\u4f1d\u5b50\u304c\u4f5c\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u5168\u5bb9\u89e3\u660e<\/a>\uff08\u57fa\u76e4B 2011 \u2013 2013\uff09<\/li>\n\n\n\n
    2. \u5316\u5b66\u91cf\u4e0d\u5747\u8861\u3092\u907f\u3051\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/a>\uff08\u57fa\u76e4B 2014-2016\uff09<\/li>\n\n\n\n
    3. \u904e\u5270\u767a\u73fe\u306b\u3088\u308a\u8f38\u9001\u30ea\u30bd\u30fc\u30b9\u306e\u904e\u8ca0\u8377\u3092\u5f15\u304d\u8d77\u3053\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4f53\u7cfb\u7684\u89e3\u6790<\/a>\uff08\u57fa\u76e4B 2017-2019\uff09<\/li>\n\n\n\n
    4. \u5909\u7570\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u9650\u754c\u767a\u73fe\u91cf\u304b\u3089\u63a2\u308b\u904e\u5270\u767a\u73fe\u306b\u3088\u308b\u5897\u6b96\u963b\u5bb3\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/a>\uff08\u57fa\u76e4B 2020-2021\uff09<\/li>\n\n\n\n
    5. \u65b0\u305f\u306a\u9650\u754c\u767a\u73fe\u7cfbgTOW2.0\u3067\u89e3\u304d\u660e\u304b\u3059\u767a\u73fe\u5236\u7d04\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u5168\u4f53\u50cf<\/a>\uff08\u57fa\u76e4B 2024-2027\uff09<\/li>\n<\/ol>\n\n\n\n

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      \"\"<\/a>
      \u91cf\u88dc\u511f\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u76ee\u7684\u3002\u79d1\u7814\u8cbb\u7533\u8acb\u66f8\u3088\u308a\u3002\u91cf\u88dc\u511f\u3068\u306f\u8a00\u308f\u306a\u3044\u3002<\/figcaption><\/figure>\n\n\n\n
      \"\"<\/a>
      \u91cf\u88dc\u511f\u3092\u691c\u51fa\u3059\u308b\u5b9f\u9a13\u306e\u30a2\u30a4\u30c7\u30a2\u3002\u3053\u3053\u3067\u907a\u4f1d\u60c5\u5831\u5834\u3067\u306e\u7d4c\u9a13\u3068\u4e88\u5099\u30c7\u30fc\u30bf\u304c\u751f\u304b\u3055\u308c\u305f\u3002<\/figcaption><\/figure>\n\n\n\n

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      \u91cf\u88dc\u511f\u306f\u5927\u5b66\u9662\u751f\u304c\u99c6\u52d5\u529b\u3068\u306a\u3063\u305f<\/h2>\n\n\n\n

      \u3053\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306f\u3001gTOW6000\u5f8c\u306e\u4f4e\u8ff7\u304b\u3089\u65b0\u305f\u306b\u5b88\u5c4b\u7814\u304c\u52d5\u304d\u51fa\u3057\u305f\u5951\u6a5f\u3060\u3063\u305f\u3002\u305d\u308c\u306f\u3053\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u304c\u5927\u5b66\u9662\u751f\u306b\u3088\u3063\u3066\u99c6\u52d5\u3055\u308c\u305f\u3082\u306e\u3060\u304b\u3089\u3060\u3002\u3053\u308c\u3092\u99c6\u52d5\u3057\u305f\u77f3\u5ddd\u6d69\u53f2\u6c0f\u306f\u5b88\u5c4b\u7814\u306b\u5916\u90e8\u304b\u3089\u6765\u305f\uff13\u540d\u306e\u535a\u58eb\u306e\u306f\u3058\u3081\u306e\uff11\u4eba\u3067\u3042\u308b\u3002\u3053\u306e\u57fa\u76e4B\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u3046\u307e\u304f\u9042\u884c\u3057\u8ad6\u6587\u5316\u306b\u307e\u3067\u3082\u3063\u3066\u884c\u3063\u305f\uff08Ishikawa PLoS Geneti. 2017<\/a>\uff09\u3002\u3053\u306e\u4ed5\u4e8b\u306f\u3001\u5b9f\u969b\u306b\u306fgTOW\u306e\u300c\u3064\u306a\u3072\u304d\u300d\u306f\u5fc5\u8981\u306a\u304f\u3001gTOW\u306e\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u304b\u3089\u751f\u307e\u308c\u305fIssue\u3092gTOW\u306e\u30ea\u30bd\u30fc\u30b9\u3092\u4f7f\u3063\u3066\u8abf\u3079\u305f\u4ed5\u4e8b\u3068\u8a00\u3046\u3053\u3068\u306b\u306f\u306a\u308b\u304c\u3001\u91cf\u88dc\u511f\u3092\u4e01\u5be7\u306b\u8abf\u3079\u305f\u4ed5\u4e8b\u3068\u3057\u3066\u8a55\u4fa1\u3092\u53d7\u3051\u3066\u3044\u308b\u3002\u77f3\u5ddd\u6c0f\u306f\u3001\u30dd\u30b9\u30c9\u30af\uff11\u5e74\u76ee\u307e\u3067\u5b88\u5c4b\u7814\u306b\u3044\u3066\u3001\u305d\u306e\u30c7\u30fc\u30bf\u3092\u3082\u3068\u306b\u91cf\u88dc\u511f\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u306e\u3082\u3046\u4e00\u672c\u306e\u8ad6\u6587\u3092\u4ed5\u4e0a\u3052\uff08Ishikawa PLoS Genet. 2020<\/a>\uff09\u3001\u7dcf\u8aac\u3082\u66f8\u3044\u305f\uff08Ishikawa Curr Genet. 2021<\/a>\uff09\u3002<\/p>\n\n\n\n

      \"\"<\/a>
      \u30bf\u30f3\u30d1\u30af\u8cea\u30ec\u30d9\u30eb\u306e\u91cf\u88dc\u511f\u3092\u4f53\u7cfb\u7684\u306b\u8abf\u3079\u305f\u8ad6\u6587\u3002Ishikawa 2017\u3088\u308a<\/figcaption><\/figure>\n\n\n\n

      \u3053\u308c\u306f\u3001\u5927\u5b66\u9662\u751f\u304c\u99c6\u52d5\u529b\u3068\u306a\u3063\u3066\u81ea\u8eab\u3067\u30c6\u30fc\u30de\u3092\u62e1\u5f35\u3055\u305b\u305f\u6210\u529f\u4f8b\u3060\u3068\u8a00\u3048\u308b\u3002\u3053\u306e\u3042\u305f\u308a\u304b\u3089\u5b88\u5c4b\u7814\u306b\u306f\u5927\u5b66\u9662\u751f\u304c\u6765\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u5f7c\u3089\u304c\u99c6\u52d5\u529b\u3068\u306a\u3063\u3066\u30c6\u30fc\u30de\u304c\u6d3e\u751f\u3057\u3066\u3044\u304f\u3053\u3068\u306b\u306a\u3063\u305f\u3002\u306a\u304a\u3001\u91cf\u88dc\u511f\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306f\u73fe\u5728\u306e\u5b88\u5c4b\u7814\u3067\u306f\u884c\u308f\u308c\u3066\u3044\u306a\u3044\u3002\u6982\u5ff5\u5b9f\u8a3c\u306f\u3067\u304d\u305f\u3057\u3001\u77f3\u5ddd\u6c0f\u306b\u6e21\u3057\u305f\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3060\u3068\u601d\u3063\u3066\u3044\u308b\u304b\u3089\u3060\u3002\u4e00\u65b9\u3001\u300c\u91cf\u88dc\u511f\u304c\u751f\u307f\u51fa\u3059\u8ca0\u8377\uff08\u91cf\u88dc\u511f\u306e\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5\uff09\u300d\u306f\u8abf\u3079\u3066\u3082\u826f\u3044\u30c6\u30fc\u30de\u3060\u3068\u601d\u3046\u3002<\/p>\n\n\n\n

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